Description

1-Pyrrolidinecarboximidamide, Monohydrochloride is a high-purity chemical building block and intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmacologically active molecules, particularly those targeting enzyme inhibition. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of drug candidates, particularly protease inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used as a building block for constructing complex heterocyclic compounds and exploring structure-activity relationships (SAR).
• Biochemical Reagent: Potential application in the development of biochemical tools and probes for studying biological pathways.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in universities and research institutes for synthetic methodology development and novel compound library generation.

Basic Information

Product Name	1-Pyrrolidinecarboximidamide, Monohydrochloride
CAS No.	49755-46-6
Molecular Formula	C5H12N3Cl
Molecular Weight	149.62 g/mol
Synonyms	1-Pyrrolidinecarboximidamide hydrochloride; Pyrrolidine-1-carboximidamide hydrochloride; 1-Aminopyrrolidine-1-carboxamidine hydrochloride; (Aminocarbonyl)(pyrrolidin-1-yl)methanimidamide hydrochloride; Amidino-pyrrolidine hydrochloride; Guanidine, N-(pyrrolidinyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboximidamide, Monohydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.