Description

n-tert-Butyl 4-Nitrophenylsulfonamide is a specialized sulfonamide derivative characterized by its tert-butyl and nitro-substituted aromatic structure. This compound matters as a versatile chemical intermediate, offering a unique sterically hindered amine group and an electron-withdrawing nitro moiety for advanced synthesis. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those requiring sterically hindered sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its bioactive sulfonamide core.
• Organic Synthesis Reagent: Acts as a protected amine source or a precursor for further functionalization (e.g., reduction to the corresponding aniline) in complex molecule assembly.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or chemical resistance properties.
• Chemical Biology Probe: Utilized in research to study enzyme inhibition or protein-ligand interactions due to its sulfonamide group's ability to mimic biological motifs.

Basic Information

Item	Details
Product Name	n-tert-Butyl 4-Nitrophenylsulfonamide
CAS No.	49690-09-7
Molecular Formula	C10H14N2O4S
Molecular Weight	258.30 g/mol
Synonyms	N-(tert-Butyl)-4-nitrobenzenesulfonamide; 4-Nitro-N-(tert-butyl)benzenesulfonamide; 4-Nitro-N-tert-butylbenzenesulfonamide; N-tert-Butyl-4-nitrobenzenesulfonamide; 1,1-Dimethylethyl(4-nitrophenyl)sulfonylamine; tert-Butyl(4-nitrophenyl)sulfonylamine; Benzenesulfonamide, N-(1,1-dimethylethyl)-4-nitro-
EINECS	Contact for details

Quality Control

Our n-tert-Butyl 4-Nitrophenylsulfonamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting key parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.