Description

2-Ethoxy-N1-Isopropyl-2-Phenylacetamidine is a specialized amidine derivative with significant utility as a key synthetic intermediate in advanced organic synthesis. Its molecular structure makes it a valuable building block for constructing complex nitrogen-containing heterocycles and active pharmaceutical ingredients (APIs). This high-purity compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its amidine functionality contributes to biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis for asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring specific nitrogen-based architectures.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways.

Basic Information

Product Name	2-Ethoxy-N1-Isopropyl-2-Phenylacetamidine
CAS No.	46499-86-9
Molecular Formula	C13H20N2O
Molecular Weight	220.31 g/mol
Synonyms	N-Isopropyl-2-ethoxy-2-phenylacetamidine; 2-Ethoxy-2-phenyl-N-(propan-2-yl)acetimidamide; 2-Phenyl-2-ethoxy-N-isopropylacetamidine; Acetamidine, 2-ethoxy-N1-isopropyl-2-phenyl-; (Z)-2-Ethoxy-N-isopropyl-2-phenylacetamidine; Amidrine derivative 46499-86-9
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-N1-Isopropyl-2-Phenylacetamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for use in pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.