Description

1,2-Dithiolane-3-Pentanoic Acid, Methyl Ester is a specialized organic sulfur compound belonging to the dithiolane class, serving as a key synthetic intermediate and a model compound for studying lipoic acid derivatives. Its value lies in its unique cyclic disulfide structure, which is crucial for research into redox biochemistry and the development of novel pharmaceuticals and nutraceuticals. This compound is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on metabolic pathways, antioxidant mechanisms, and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of lipoic acid analogs and other bioactive molecules targeting oxidative stress.
• Biochemical Research: Used as a reference standard and probe in studies of mitochondrial metabolism, antioxidant mechanisms, and thiol-disulfide exchange reactions.
• Nutraceutical Development: Serves as a precursor or model compound in the research and development of advanced dietary supplements.
• Organic Synthesis: Employed as a versatile intermediate for constructing complex molecules containing disulfide or dithiolane functional groups.
• Material Science: Investigated for potential use in creating novel polymers or materials with redox-active properties.

Basic Information

Product Name	1,2-Dithiolane-3-Pentanoic Acid, Methyl Ester
CAS No.	46236-19-5
Molecular Formula	C9H14O2S2
Molecular Weight	218.34 g/mol
Synonyms	Methyl 1,2-dithiolane-3-pentanoate; Methyl 5-(1,2-dithiolan-3-yl)pentanoate; 3-Pentanoic acid, 1,2-dithiolane-, methyl ester; Lipoic acid methyl ester; 6,8-Thioctic acid methyl ester; α-Lipoic acid methyl ester; (±)-α-Lipoic acid methyl ester; DL-α-Lipoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1,2-Dithiolane-3-Pentanoic Acid, Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.