Description

n-(2,6-Difluoro-Benzyl)-Guanidine is a specialized guanidine derivative featuring a difluorinated benzyl group, which imparts unique chemical and physical properties. This compound is valued as a key synthetic intermediate and building block in advanced organic synthesis, particularly for creating molecules with enhanced biological activity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, receptor modulators, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the difluoro-benzyl moiety can influence bioavailability and environmental persistence.
• Chemical Synthesis Reagent: Serves as a versatile guanidination agent for introducing the guanidine functional group into complex molecular architectures in organic and process chemistry.
• Bioconjugation & Probe Development: Utilized in biochemical research for modifying peptides, proteins, or other biomolecules to create probes, tags, or affinity ligands.
• Material Science Precursor: Potential use as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced functional materials.

Basic Information

Product Name	n-(2,6-Difluoro-Benzyl)-Guanidine
CAS No.	46167-97-9
Molecular Formula	C8H9F2N3
Molecular Weight	185.18 g/mol
Synonyms	1-[(2,6-Difluorophenyl)methyl]guanidine; Guanidine, N-[(2,6-difluorophenyl)methyl]-; 2,6-Difluorobenzylguanidine; (2,6-Difluorobenzyl)guanidine; N-(2,6-Difluorobenzyl)guanidine; 46167-97-9; DFBG
EINECS	Contact for details

Quality Control

Our n-(2,6-Difluoro-Benzyl)-Guanidine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.