Description

2-Thienylzinc Bromide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation, specifically in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing thiophene-containing bioactive molecules and active pharmaceutical ingredients (APIs) via cross-coupling.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that incorporate the thienyl moiety for enhanced activity.
• Material Science & Organic Electronics: Serves as a precursor for synthesizing conjugated polymers and small molecules for organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand & Catalyst Preparation: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Fine Chemical & Specialty Chemical Production: Facilitates the manufacture of complex fragrance, flavor, and dye intermediates.
• Academic & Process R&D: A valuable tool for methodological development and scaling novel synthetic routes in research laboratories.

Basic Information

Product Name	2-Thienylzinc Bromide
CAS No.	45438-80-0
Molecular Formula	C4H3BrSZn
Molecular Weight	236.41 g/mol
Synonyms	2-Thienylzinc bromide solution; Thiophen-2-ylzinc bromide; Zinc, bromo(2-thienyl)-; (2-Thienyl)zinc bromide; Bromo(2-thienyl)zinc; 2-Thienylzinc bromide (Thf); Thiophene-2-zinc bromide
EINECS	Contact for details

Quality Control

Our 2-Thienylzinc Bromide is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including titration for zinc content and GC/HPLC analysis for purity and solvent composition, to ensure consistency and reliability. Certificates of Analysis (COA) with detailed batch-specific data are provided to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated area. Due to its moisture-sensitive and easily oxidized nature, the container should be kept sealed and allowed to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (in THF)	0.5 M (Typical)
Assay (Zinc by Titration)	≥ 95%
Purity (GC/HPLC)	Contact for details
Water Content (Karl Fischer)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.