Description

[1-(Aminomethyl)Cyclopropyl]Methanol is a versatile bifunctional organic compound featuring both an amino and a hydroxyl group on a strained cyclopropane ring, making it a valuable chiral building block for complex synthesis. This unique structure is critical for introducing the constrained cyclopropyl moiety into target molecules, which can significantly alter their biological activity and physicochemical properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in areas like protease inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in constructing advanced intermediates for new generation herbicides, fungicides, and insecticides where the cyclopropane ring enhances stability and bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling high enantioselectivity in critical bond-forming reactions.
• Peptidomimetics and Bioisosteres: The aminomethyl cyclopropanol structure is valuable for creating conformationally restricted peptide analogs and bioisosteric replacements in medicinal chemistry.
• Material Science Research: Employed in the synthesis of specialized monomers or cross-linkers for polymers with unique mechanical or chemical properties.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	[1-(Aminomethyl)Cyclopropyl]Methanol
CAS No.	45434-02-4
Molecular Formula	C5H11NO
Molecular Weight	101.15 g/mol
Synonyms	(1-(Aminomethyl)cyclopropyl)methanol; 1-(Aminomethyl)cyclopropanemethanol; (Aminomethyl)cyclopropylmethanol; Cyclopropanemethanol, 1-(aminomethyl)-; 1-Cyclopropyl-2-aminoethanol (tautomeric form); 2-Amino-1-cyclopropylethanol; (1-Cyclopropyl-2-hydroxyethyl)amine; Amino-functionalized cyclopropanol derivative
EINECS	Contact for details

Quality Control

Our [1-(Aminomethyl)Cyclopropyl]Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.