Description

n-Hexadecanoyl-L-Valine is a high-purity, synthetic lipoamino acid conjugate, combining a long-chain palmitic acid (hexadecanoic acid) moiety with the essential amino acid L-valine. This molecular design is critical for applications requiring enhanced lipophilicity and targeted bioactivity, bridging the gap between fatty acid and peptide chemistries. It serves as a valuable building block and intermediate for researchers and manufacturers in the pharmaceutical, cosmetic, and advanced material sectors, where precise molecular structure dictates function.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of lipopeptide prodrugs and novel active pharmaceutical ingredients (APIs) designed for improved membrane permeability and bioavailability.
• Cosmetic Actives: Used in the formulation of high-performance skincare products as a biomimetic lipid, supporting skin barrier function and enhancing the delivery of active compounds.
• Bioconjugation & Linker Chemistry: Serves as a versatile linker molecule for coupling hydrophobic tags to peptides, proteins, or other biomolecules in drug discovery and diagnostic assay development.
• Surfactant & Emulsifier Research: Investigated for its amphiphilic properties in creating novel, biocompatible surfactants and stabilizers for nanoemulsions and lipid-based delivery systems.
• Biochemical Research: Essential standard and reagent in metabolic studies, enzyme substrate research, and the investigation of lipid-protein interactions.
• Material Science: Building block for synthesizing functional polymers and smart materials with tailored surface properties and self-assembly characteristics.

Basic Information

Product Name	n-Hexadecanoyl-L-Valine
CAS No.	45287-42-1
Molecular Formula	C21H41NO3
Molecular Weight	355.56 g/mol
Synonyms	Palmitoyl-L-valine; L-Valine, N-(1-oxohexadecyl)-; N-Hexadecanoylvaline; N-Palmitoyl-L-valine; Hexadecanoylvaline; Palmitic acid valine amide; Valine palmitamide; (2S)-2-[(1-Oxohexadecyl)amino]-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Every batch of n-Hexadecanoyl-L-Valine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, enantiomeric purity, and impurity profiles. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.