Description

Boc-L-Selenomethionine is a protected derivative of the essential amino acid methionine, where the selenium atom replaces sulfur. This compound is a crucial building block in peptide synthesis and biochemical research, offering enhanced stability for the selenomethionine residue during complex coupling reactions. It is primarily utilized by pharmaceutical R&D teams, peptide chemists, and academic researchers developing novel therapeutics and studying selenium's role in biological systems.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled incorporation of selenomethionine into synthetic peptides and proteins.
• Selenoprotein Research: Used in the study of selenoprotein structure, function, and biosynthesis, including the production of selenomethionine-labeled proteins for X-ray crystallography.
• Pharmaceutical Intermediate: Serves as a critical precursor in the development of novel drug candidates, particularly those targeting oxidative stress or utilizing selenium's unique redox properties.
• Bioconjugation & Probe Development: Facilitates the site-specific introduction of selenium for creating bioconjugates, imaging probes, or catalysts.
• Nutritional & Biochemical Studies: Employed in research investigating selenium metabolism, bioavailability, and its role as an antioxidant in biological systems.

Basic Information

Product Name	Boc-L-Selenomethionine
CAS No.	45172-44-9
Molecular Formula	C10H19NO4Se
Molecular Weight	296.22 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-4-(methylselanyl)butanoic acid; N-(tert-Butoxycarbonyl)-L-selenomethionine; Boc-SeMet; Boc-L-Selenomethionine; N-Boc-L-selenomethionine; N-α-Boc-L-selenomethionine; tert-Butyloxycarbonyl-L-selenomethionine; L-Selenomethionine, N-Boc-
EINECS	Contact for details

Quality Control

Our Boc-L-Selenomethionine is manufactured under strict quality control protocols to ensure high chemical purity and consistency suitable for sensitive research and synthesis applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for pharmaceutical intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated place. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.