Description

Methanethiosulfonate is a versatile organosulfur compound widely utilized as a key reagent in chemical synthesis and bioconjugation. Its primary value lies in its ability to introduce thiol-reactive groups, enabling the site-specific modification of proteins, peptides, and other biomolecules under mild conditions. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly for developing antibody-drug conjugates (ADCs), protein labeling, and creating functionalized materials.

Application

• Bioconjugation Reagent: For the site-specific modification of cysteine residues in proteins and antibodies, crucial for ADC development and diagnostic probe creation.
• Chemical Crosslinking: Used to create disulfide bonds or introduce functional handles for linking molecules in material science and polymer chemistry.
• Protecting Group Chemistry: Acts as a protective agent for thiol groups during multi-step organic synthesis.
• Surface Functionalization: Modifies gold nanoparticles, biosensors, and other surfaces to create reactive interfaces for biomolecule immobilization.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of more complex sulfur-containing active pharmaceutical ingredients (APIs).
• Research & Development: A fundamental tool in academic and industrial R&D for studying protein structure, function, and interactions.

Basic Information

Product Name	Methanethiosulfonate
CAS No.	44059-82-7
Molecular Formula	CH4O2S2
Molecular Weight	112.17 g/mol
Synonyms	Methyl methanethiosulfonate; Methanesulfonothioic acid methyl ester; Methylthiosulfonylmethane; Methyl methanesulfonothioate; MTS; MMTS; Methyl thiosulfonate; Methyl sulfenyl sulfonate
EINECS	Contact for details

Quality Control

Our Methanethiosulfonate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.