Description

2-(Iodomethyl)Tetrahydropyran is a versatile halogenated heterocyclic building block used in advanced organic synthesis. Its value lies in its reactive iodomethyl group, which facilitates key carbon-carbon bond-forming reactions and functional group transformations under mild conditions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing tetrahydropyranyl-protected functional groups or creating chiral centers.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the tetrahydropyran moiety contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel polymers and functional materials with specific thermal or chemical properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in various metal-catalyzed cross-coupling reactions, such as Negishi or Kumada couplings.
• Protecting Group Chemistry: The tetrahydropyranyl group can be used to protect alcohols, with the iodomethyl handle allowing for further elaboration or deprotection strategies.

Basic Information

Product Name	2-(Iodomethyl)Tetrahydropyran
CAS No.	43216-12-2
Molecular Formula	C6H11IO
Molecular Weight	226.06 g/mol
Synonyms	2-(Iodomethyl)oxane; Tetrahydropyran-2-ylmethyl iodide; 2-Iodomethyltetrahydropyran; 2-(IODOMETHYL)TETRAHYDRO-2H-PYRAN; Oxane, 2-(iodomethyl)-; 2H-Pyran, tetrahydro-2-(iodomethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-(Iodomethyl)Tetrahydropyran is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.