Description

2-Chloromethyl-1,4-Naphthoquinone is a versatile and reactive chloromethylated derivative of 1,4-naphthoquinone, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its ability to introduce functionalized quinone moieties into target molecules, enabling the development of compounds with specific biological or material properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel therapeutic agents, particularly in anticancer and antimicrobial research programs.
• Agrochemical Synthesis: Used in the development of next-generation fungicides, herbicides, and plant growth regulators.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with unique redox or electronic properties.
• Dye and Pigment Precursor: Intermediate in the synthesis of advanced quinone-based dyes and organic pigments.
• Material Science Research: Employed in the development of organic semiconductors, charge-transfer complexes, and other electronic materials.
• Biochemical Probe Development: Useful for synthesizing activity-based probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	2-Chloromethyl-1,4-Naphthoquinone
CAS No.	43027-41-4
Molecular Formula	C11H7ClO2
Molecular Weight	206.62 g/mol
Synonyms	2-(Chloromethyl)-1,4-naphthalenedione; 2-(Chloromethyl)naphthoquinone; 1,4-Naphthoquinone, 2-(chloromethyl)-; 2-Chloromethyl-1,4-dihydro-1,4-naphthoquinone; NSC 403169; Menadione, 2-chloromethyl derivative
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-1,4-Naphthoquinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.