Description

Dimethyl 2-(Hydroxyimino)Malonate is a versatile organic synthon characterized by its reactive malonate ester and oxime functional groups. This compound is of significant value in fine chemical synthesis, serving as a key building block for constructing complex heterocyclic and pharmaceutical intermediates. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing nitrogen heterocycles like isoxazoles, pyrazoles, and other fused ring systems.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and insecticides, where its reactive sites allow for the introduction of specific bioactive moieties.
• Heterocyclic Chemistry: Serves as a fundamental starting material for [3+2] cycloaddition reactions and other ring-forming processes to generate a diverse library of five-membered heterocyclic compounds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities for screening.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of complex organic molecules for specialized dyes and functional pigments.
• Ligand and Chelator Synthesis: Acts as a building block for creating novel polydentate ligands used in catalysis and metal complexation.

Basic Information

Product Name	Dimethyl 2-(Hydroxyimino)Malonate
CAS No.	42937-74-6
Molecular Formula	C5H7NO5
Molecular Weight	161.11 g/mol
Synonyms	Dimethyl (hydroxyimino)propanedioate; Dimethyl 2-(Hydroxyimino)propanedioate; 2-(Hydroxyimino)malonic Acid Dimethyl Ester; Propanedioic acid, 2-(hydroxyimino)-, dimethyl ester; Oxomalonic acid dimethyl ester oxime; DMHM
EINECS	Contact for details

Quality Control

Our Dimethyl 2-(Hydroxyimino)Malonate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.