Description

o-Allylbromobenzene CAS NO 42918-20-7 is a versatile aromatic bromo compound featuring an allyl substituent in the ortho position, serving as a valuable bifunctional building block in advanced organic synthesis. Its molecular structure combines the reactivity of an aryl bromide for cross-coupling reactions with the versatility of an allyl group for further functionalization, enabling the construction of complex molecular architectures. This intermediate is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring ortho-substituted biphenyl or heterocyclic cores via Suzuki-Miyaura or other palladium-catalyzed cross-couplings.
• Agrochemical Synthesis: Used in building blocks for crop protection agents, where the bromine and allyl groups allow for sequential introduction of different functional moieties.
• Ligand and Catalyst Development: Serves as a starting material for the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis.
• Material Science Research: Employed in the polymerization and functionalization of monomers to create polymers with specific aromatic and alkenyl properties for advanced materials.
• Chemical Biology Probes: Useful for introducing photoaffinity labels (via the allyl group) or bioconjugation handles into molecules for studying biological interactions.
• Fine Chemical Production: Intermediate for manufacturing dyes, flavors, fragrances, and other high-value specialty chemicals requiring precise substitution patterns.

Basic Information

Product Name	o-Allylbromobenzene
CAS No.	42918-20-7
Molecular Formula	C9H9Br
Molecular Weight	197.07 g/mol
Synonyms	1-Bromo-2-allylbenzene; 2-Allylbromobenzene; 2-Allyl-1-bromobenzene; (2-Bromophenyl)propene; ortho-Allylbromobenzene; Bromo(2-allyl)benzene; 2-Bromoallylbenzene
EINECS	Contact for details

Quality Control

Every batch of o-Allylbromobenzene is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.