Description

3-Nitroadamantane-1-Carboxylic Acid is a high-value, functionalized adamantane derivative that serves as a critical building block in advanced organic synthesis. Its unique rigid cage structure and strategically placed nitro and carboxylic acid functional groups make it an essential precursor for developing novel materials and pharmaceuticals. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging the adamantane scaffold's lipophilicity and metabolic stability.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, where the adamantane core can enhance compound stability and bioavailability.
• Advanced Material Synthesis: Serves as a monomer or cross-linking agent for creating high-performance polymers, resins, and specialty coatings with enhanced thermal and chemical resistance.
• Ligand and Catalyst Development: The carboxylic acid group allows for functionalization to create novel chelating ligands or organocatalysts for asymmetric synthesis.
• Academic & Industrial R&D: Fundamental research tool for studying structure-activity relationships (SAR) and reaction mechanisms involving polycyclic frameworks.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex specialty chemicals for electronics and nanotechnology applications.

Basic Information

Product Name	3-Nitroadamantane-1-Carboxylic Acid
CAS No.	42711-76-2
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	1-Carboxy-3-nitroadamantane; 3-Nitro-1-adamantanecarboxylic Acid; Adamantane-1-carboxylic acid, 3-nitro-; 3-Nitrotricyclo[3.3.1.13,7]decane-1-carboxylic Acid; 3-Nitroadamantane-1-carboxylic acid; 3-Nitro-1-carboxyadamantane
EINECS	Contact for details

Quality Control

Our 3-Nitroadamantane-1-Carboxylic Acid is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and FTIR, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.