Description

n-Me-Val-Obzl p-Tosylate is a specialized chemical intermediate, specifically a protected amino acid derivative, with the CAS number 42492-62-6. This compound is critical for advanced organic synthesis, particularly in the construction of complex peptide chains and other bioactive molecules where precise stereochemistry and functional group protection are required. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and high-value fine chemicals.

Application

• Peptide Synthesis: Serves as a key building block (N-methyl valine derivative) in solid-phase and solution-phase peptide synthesis for research and pharmaceutical development.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring specific amino acid modifications.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibitors, receptor ligands, and other biologically active peptides.
• Fine Chemical Production: Acts as a precursor in the manufacture of complex, high-purity specialty chemicals for various advanced applications.
• Protecting Group Chemistry: The Obzl (benzyl ester) and tosylate groups make it a valuable reagent in multi-step synthetic routes requiring orthogonal protection strategies.

Basic Information

Product Name	n-Me-Val-Obzl p-Tosylate
CAS No.	42492-62-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Methyl-L-valine benzyl ester p-toluenesulfonate salt; L-Valine, N-methyl-, benzyl ester, 4-methylbenzenesulfonate; Benzyl N-methyl-L-valinate p-toluenesulfonate; N-Me-Val-OBzl Tosylate; N-Methylvaline benzyl ester tosylate; 42492-62-6; Bzl-N-Me-Val-OTs
EINECS	Contact for details

Quality Control

Our n-Me-Val-Obzl p-Tosylate is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, chiral purity, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.