Description

2-Amino-5-(2-Bromoacrylamido)Benzenesulfonic Acid is a specialized sulfonic acid derivative that serves as a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both a reactive bromoacrylamido group and a sulfonic acid moiety, makes it a critical building block for creating functional molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and specialty chemical industries for applications in drug discovery and the development of novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring sulfonamide or vinyl functionality.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other bioconjugates due to its reactive bromoacrylamido group for selective coupling.
• Polymer Chemistry: Monomer or cross-linking agent for synthesizing functional polymers, ion-exchange resins, and hydrogels with sulfonic acid groups.
• Dye and Pigment Synthesis: Intermediate in the production of specialized azo dyes and pigments where the sulfonic acid group enhances water solubility.
• Material Science Research: Building block for creating novel organic frameworks, surface modifiers, and catalysts.
• Agrochemical Development: Potential intermediate in the synthesis of new generation herbicides or plant growth regulators.

Basic Information

Product Name	2-Amino-5-(2-Bromoacrylamido)Benzenesulfonic Acid
CAS No.	42486-84-0
Molecular Formula	C9H9BrN2O4S
Molecular Weight	321.15 g/mol
Synonyms	5-[(2-Bromoacryloyl)amino]-2-aminobenzenesulfonic Acid; 2-Amino-5-[(2-bromo-1-oxo-2-propen-1-yl)amino]benzenesulfonic Acid; Benzenesulfonic acid, 2-amino-5-[(2-bromo-1-oxo-2-propenyl)amino]-; 2-Amino-5-(2-bromoacryloylamino)benzenesulfonic Acid; 2-Bromo-N-(4-amino-3-sulfophenyl)acrylamide
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(2-Bromoacrylamido)Benzenesulfonic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), residual solvents, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.