Description

cis-2-Amino-Cycloheptanecarboxylic Acid is a specialized, non-proteinogenic amino acid derivative featuring a seven-membered cycloalkane ring. This compound is a valuable chiral building block in advanced organic synthesis, prized for its constrained conformation which can influence the secondary structure of peptide mimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and as a ligand in asymmetric catalysis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel peptide-based drugs and bioactive compounds.
• Peptidomimetics Research: Used to introduce conformational constraints into peptide chains, aiding in the study of structure-activity relationships (SAR) and metabolic stability.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce enantioselectivity.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms or protein-protein interactions.
• Academic & Industrial R&D: Employed in fundamental organic chemistry research and process development for complex molecule synthesis.

Basic Information

Product Name	cis-2-Amino-Cycloheptanecarboxylic Acid
CAS No.	42418-83-7
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1S,2R)-2-Aminocycloheptanecarboxylic acid; cis-2-Aminocycloheptane-1-carboxylic acid; cis-2-Amino-1-cycloheptanecarboxylic acid; 2-Aminocycloheptanecarboxylic acid, cis-; 2-Azabicyclo[4.1.0]heptane-3-carboxylic acid derivative (related structure); Cycloheptane amino acid
EINECS	Contact for details

Quality Control

Our cis-2-Amino-Cycloheptanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.