Description

1-Propanol, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, 4-Methylbenzenesulfonate, (2S)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for ensuring the biological activity and efficacy of final products. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for optimal activity.
• Asymmetric Catalysis Research: Serves as a starting material or ligand precursor in the development of new catalytic systems for stereoselective reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require enantiomerically pure components.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new C-O and C-S bond-forming reactions.

Basic Information

Product Name	1-Propanol, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, 4-Methylbenzenesulfonate, (2S)-
CAS No.	42274-61-3
Molecular Formula	C15H22O5S
Molecular Weight	314.40 g/mol
Synonyms	(2S)-2-[(Tetrahydro-2H-pyran-2-yl)oxy]-1-propanol 4-methylbenzenesulfonate; (S)-2-[(Tetrahydro-2H-pyran-2-yl)oxy]propyl p-toluenesulfonate; (S)-THP-Protected Propyl Tosylate; (S)-1-(Tetrahydro-2H-pyran-2-yloxy)propan-2-yl 4-methylbenzenesulfonate; (2S)-2-(Tetrahydro-2H-pyran-2-yloxy)propyl p-toluenesulfonate; (S)-2-(THP-O)Propyl Tosylate; Chiral THP-Protected Tosylate Ester
EINECS	Contact for details

Quality Control

Our production of 1-Propanol, 2-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-, 4-Methylbenzenesulfonate, (2S)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to confirm identity and specification compliance. Certificates of Analysis (COA) detailing all test results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.