Description

4-(3-Chlorophenyl)-3-Thiosemicarbazide is a specialized organic compound belonging to the thiosemicarbazide class, featuring a chlorophenyl substituent. This structure makes it a valuable intermediate and building block in advanced chemical synthesis, particularly for the development of heterocyclic compounds and active pharmaceutical ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors seeking to develop new molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel heterocyclic compounds with potential therapeutic activities.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, such as fungicides or herbicides.
• Coordination Chemistry: Serves as a versatile ligand for metal complexation, useful in catalysis and material science.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the thiosemicarbazide moiety into more complex molecular architectures.
• Analytical Reagent: Potential use as a derivatization agent or chelating agent in specific analytical methodologies.

Basic Information

Product Name	4-(3-Chlorophenyl)-3-Thiosemicarbazide
CAS No.	42135-76-2
Molecular Formula	C7H8ClN3S
Molecular Weight	201.68 g/mol
Synonyms	1-(3-Chlorophenyl)thiosemicarbazide; 3-Chlorophenylthiosemicarbazide; N-(3-Chlorophenyl)hydrazinecarbothioamide; 3-Chloro-benzenecarbothioic acid hydrazide; Thiosemicarbazide, N-(3-chlorophenyl)-; 1-(3-Chlorophenyl)-2-thiosemicarbazide
EINECS	Contact for details

Quality Control

Our 4-(3-Chlorophenyl)-3-Thiosemicarbazide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents, supporting compliance with cGMP and relevant ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.