Description

α-Methylpyrrolidine-1-Ethanol is a versatile organic compound featuring a pyrrolidine ring substituted with both methyl and hydroxymethyl groups. This unique structure makes it a valuable intermediate and building block in advanced chemical synthesis, offering reactivity at both the nitrogen and alcohol functionalities. It is particularly sought after by the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from catalyst synthesis to the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring chiral pyrrolidine-based structures.
• Catalyst & Ligand Synthesis: Used to prepare nitrogen-containing ligands for transition metal catalysts used in asymmetric synthesis and other fine chemical processes.
• Agrochemical Production: Serves as a precursor in the manufacture of certain herbicides, fungicides, and plant growth regulators.
• Corrosion Inhibitor Formulation: Incorporated into formulations for industrial cooling water systems and metalworking fluids.
• Polymer & Resin Modifier: Acts as a monomer or curing agent modifier to impart specific properties like flexibility or adhesion in specialty polymers.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	α-Methylpyrrolidine-1-Ethanol
CAS No.	42122-41-8
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	1-(2-Hydroxyethyl)-2-methylpyrrolidine; 2-Methyl-1-(2-hydroxyethyl)pyrrolidine; 2-Methylpyrrolidine-1-ethanol; N-(2-Hydroxyethyl)-2-methylpyrrolidine; 1-(2-Hydroxyethyl)-2-methylazolidine; 2-Methyl-N-(2-hydroxyethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our α-Methylpyrrolidine-1-Ethanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (by GC/HPLC), water content, and specific impurity profiles. Our quality commitment ensures the material meets the stringent requirements for use in pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Refractive Index (n20/D)	1.470 - 1.480
Density (g/mL, 20°C)	0.950 - 0.980

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.