Description

2-Methoxycyclobutan-1-One is a versatile organic building block featuring a functionalized cyclobutane ring. This compound matters for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical producers for applications requiring constrained ring systems.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides that require specific stereochemistry for enhanced efficacy.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of polymers and liquid crystals with unique structural properties derived from the strained cyclobutane ring.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex, musky, or woody odorant molecules.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Product Name	2-Methoxycyclobutan-1-One
CAS No.	42083-01-2
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	2-Methoxycyclobutanone; Methoxycyclobutanone; 1-Methoxycyclobutan-2-one; Cyclobutanone, 2-methoxy-; 2-Methoxy-1-cyclobutanone
EINECS	Contact for details

Quality Control

Our 2-Methoxycyclobutan-1-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.