Description

Tri-tert-Butylmethanol is a highly sterically hindered tertiary alcohol with the CAS number 41902-42-5. This unique molecular structure makes it a valuable and versatile building block in advanced organic synthesis and materials science research. It is particularly sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries. Its applications leverage its significant steric bulk to influence reaction pathways and material properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, where its bulky groups can be used to modulate bioavailability and metabolic stability.
• Ligand Synthesis for Catalysis: Used to create sterically demanding phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysts, enhancing selectivity in cross-coupling and hydrogenation reactions.
• Polymer Modification: Acts as a chain transfer agent or terminating group to control polymer molecular weight and introduce steric hindrance into polymer backbones for specialty materials.
• Agrochemical Research: Employed in developing novel active ingredients where the tert-butyl groups can improve lipophilicity and environmental persistence.
• Organic Synthesis Building Block: Utilized in constructing complex, three-dimensional molecular architectures for fragrances, flavors, and advanced organic materials.
• Academic & Industrial R&D: A fundamental reagent for studying steric effects in reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Tri-tert-Butylmethanol
CAS No.	41902-42-5
Molecular Formula	C13H28O
Molecular Weight	200.36 g/mol
Synonyms	2,2-Di-tert-butyl-1,1-dimethylethanol; Tris(tert-butyl)methanol; 1,1-Dimethyl-2,2-di-tert-butylethanol; 2,2-Di-tert-butylpropan-1-ol; Tri-tert-butylcarbinol; (CH3)3C-C(OH)(C(CH3)3)2; TTBM
EINECS	Contact for details

Quality Control

Our Tri-tert-Butylmethanol is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Melting Point	~86-90 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.