Description

2-Amino-1-(4-tert-Butylphenyl)Ethan-1-Ol is a versatile chiral amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an aromatic tert-butyl group and amino-ethanol functionality, makes it a valuable intermediate for creating complex molecules with specific stereochemistry. This compound is primarily utilized by research and development chemists in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Fine Chemical Synthesis: Serves as a crucial building block for the preparation of complex agrochemicals, dyes, and specialty polymers requiring specific stereocenters.
• Research & Development: Employed in academic and industrial R&D for methodological studies in organic synthesis and the exploration of new chemical entities.
• Resolution Agent: Can be utilized as a resolving agent for the separation of racemic mixtures of acids due to its chiral amine group.

Basic Information

Product Name	2-Amino-1-(4-tert-Butylphenyl)Ethan-1-Ol
CAS No.	41870-80-8
Molecular Formula	C₁₂H₁₉NO
Molecular Weight	193.29 g/mol
Synonyms	2-Amino-1-(4-tert-butylphenyl)ethanol; 1-(4-tert-Butylphenyl)-2-aminoethanol; 4-tert-Butyl-β-hydroxy-β-phenethylamine; 2-Amino-1-(4-(1,1-dimethylethyl)phenyl)ethanol; (RS)-2-Amino-1-(4-tert-butylphenyl)ethanol; 1-(4-tert-Butylphenyl)-2-aminoethan-1-ol; 4-tert-Butylphenylethanolamine; Amino alcohol intermediate 41870-80-8
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4-tert-Butylphenyl)Ethan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.