Description

4-Methyl-3-(Methylthio)-5-(5-Nitrofuran-2-Yl)-4H-1,2,4-Triazole is a heterocyclic organic compound featuring a unique triazole core fused with a nitrofuran moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's structure is conducive to further functionalization, enabling the development of targeted bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antimicrobial, antifungal, and antiparasitic agents, leveraging the bioactive nitrofuran and triazole pharmacophores.
• Agrochemical Research: Serves as a core scaffold for developing new generations of fungicides and herbicides with potential for enhanced efficacy and selectivity.
• Medicinal Chemistry & Drug Discovery: A crucial building block for constructing compound libraries aimed at high-throughput screening against various biological targets.
• Chemical Synthesis: Used in heterocyclic chemistry for the preparation of more complex, fused-ring systems with potential application in material science.
• Biochemical Research: May be employed as a probe or inhibitor in enzymatic studies due to its potential interaction with specific protein sites.

Basic Information

Product Name	4-Methyl-3-(Methylthio)-5-(5-Nitrofuran-2-Yl)-4H-1,2,4-Triazole
CAS No.	41735-55-1
Molecular Formula	C8H8N4O3S
Molecular Weight	240.24 g/mol
Synonyms	5-(5-Nitro-2-furyl)-4-methyl-3-(methylthio)-4H-1,2,4-triazole; 3-Methylthio-4-methyl-5-(5-nitrofurfurylideneamino)-1,2,4-triazole; 4-Methyl-3-methylthio-5-(5-nitrofuran-2-yl)-1,2,4-triazole; 5-(5-Nitrofuran-2-yl)-4-methyl-3-(methylsulfanyl)-4H-1,2,4-triazole; 1,2,4-Triazole, 4-methyl-3-(methylthio)-5-(5-nitrofuran-2-yl)-; 41735-55-1; 4H-1,2,4-Triazole, 4-methyl-3-(methylthio)-5-(5-nitrofuran-2-yl)-
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-3-(Methylthio)-5-(5-Nitrofuran-2-Yl)-4H-1,2,4-Triazole adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.