Description

2-Hydroxy-3-Methyl-Pentanoic Acid Methyl Ester is a chiral ester derivative of a branched-chain hydroxy acid, serving as a versatile intermediate in advanced organic synthesis. Its value lies in its functional groups, which make it a critical building block for constructing complex molecules with specific stereochemistry. This compound is essential for R&D and production in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fragrances.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used as a building block for producing specialty chemicals, including flavors, fragrances, and agrochemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems.
• Polymer Modification: Acts as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Academic & Industrial R&D: Serves as a standard or starting material in chemical research for method development and compound library synthesis.

Basic Information

Product Name	2-Hydroxy-3-Methyl-Pentanoic Acid Methyl Ester
CAS No.	41654-19-7
Molecular Formula	C₈H₁₆O₃
Molecular Weight	160.21 g/mol
Synonyms	Methyl 2-Hydroxy-3-Methylpentanoate; Methyl 3-Methyl-2-hydroxypentanoate; 2-Hydroxy-3-methylpentanoic acid methyl ester; 3-Methyl-2-hydroxypentanoic Acid Methyl Ester; Methyl (2R,3S)-2-hydroxy-3-methylpentanoate (stereoisomer); Methyl (2S,3R)-2-hydroxy-3-methylpentanoate (stereoisomer); Methyl 2-hydroxy-3-methylvalerate
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Methyl-Pentanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Specific isomer available upon request)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.