Description

(1R,E)-2,2-Dimethyl-3(2-Methylprop-1-Enyl)-Cyclopropane-1-Carbonic Acid Ethyl Ester is a high-purity, stereochemically defined cyclopropane derivative, a key chiral intermediate in advanced organic synthesis. Its precise stereochemistry and functional group arrangement make it a valuable building block for creating complex molecules with specific biological activity. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active ingredients requiring a defined three-dimensional structure.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, anti-inflammatory, or other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and insecticides, where the cyclopropane ring and specific stereochemistry contribute to biological efficacy and selectivity.
• Fine Chemical Production: Serves as a specialized building block in the manufacture of flavors, fragrances, and other high-value fine chemicals requiring precise molecular architecture.
• Academic & Industrial R&D: A valuable reagent for methodological development in asymmetric synthesis and for exploring new chemical spaces in medicinal chemistry programs.
• Material Science Precursor: Potential use in the synthesis of specialized monomers or ligands for advanced polymeric materials or catalytic systems.

Basic Information

Item	Details
Product Name	(1R,E)-2,2-Dimethyl-3(2-Methylprop-1-Enyl)-Cyclopropane-1-Carbonic Acid Ethyl Ester
CAS No.	41641-27-4
Molecular Formula	C12H20O2
Molecular Weight	196.29 g/mol
Synonyms	Ethyl (1R,trans)-2,2-Dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; (1R,trans)-Chrysanthemic acid ethyl ester; (+)-trans-Ethyl chrysanthemate; (1R,trans)-Ethyl 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate; Ethyl (1R,3E)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate; (1R,E)-Ethyl chrysanthemate; trans-(1R)-Ethyl chrysanthemate
EINECS	Contact for details

Quality Control

Our (1R,E)-2,2-Dimethyl-3(2-Methylprop-1-Enyl)-Cyclopropane-1-Carbonic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/GC), to ensure high enantiomeric excess (ee) and chemical purity meet rigorous standards. Certificates of Analysis (COA) with full specification data are provided for every shipment, ensuring traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent contamination and quality degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.