Description

3-Acetylsulfanylpropanoic Acid is a versatile sulfur-containing organic acid derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a carboxylic acid and a protected thiol (acetyl sulfide) group, makes it a valuable reagent for introducing sulfur functionalities and constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications requiring controlled thiol chemistry.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing thioether or disulfide linkages.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics where a protected cysteine-like side chain is required.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators that incorporate sulfur-based functional groups.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing sulfur-containing ligands used in metal catalysis and coordination chemistry.
• Polymer Modification: Employed to introduce thiol-reactive sites or pendant carboxylic acid groups into polymer backbones for functional materials.
• Bioconjugation Chemistry: Useful in creating linkers and cross-linking agents for protein and antibody-drug conjugate (ADC) development.

Basic Information

Product Name	3-Acetylsulfanylpropanoic Acid
CAS No.	41345-70-4
Molecular Formula	C5H8O3S
Molecular Weight	148.18 g/mol
Synonyms	3-(Acetylthio)propanoic Acid; 3-(Acetylsulfanyl)propionic Acid; 3-Mercaptopropionic Acid Acetate; Acetyl-3-mercaptopropionic Acid; β-Acetylthiopropionic Acid; S-Acetyl-3-mercaptopropionic Acid; 3-Acetylthiopropanoic Acid; 3-(Acetylmercapto)propanoic Acid
EINECS	Contact for details

Quality Control

Our 3-Acetylsulfanylpropanoic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.