Description

3-Chloro-4-Iodonitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and nitro substituents, makes it an exceptionally versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and anti-infective applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where its halogenated aromatic core is incorporated into bioactive molecules.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine atom, enabling the formation of complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a standard reagent for exploring new synthetic methodologies and reaction pathways.
• Dye and Pigment Intermediate: Functions as a starting material for the synthesis of complex, halogenated dyes and organic pigments.

Basic Information

Product Name	3-Chloro-4-Iodonitrobenzene
CAS No.	41252-96-4
Molecular Formula	C6H3ClINO2
Molecular Weight	283.45 g/mol
Synonyms	1-Chloro-2-iodo-5-nitrobenzene; 3-Chloro-4-iodonitrobenzene; 2-Iodo-5-nitrochlorobenzene; 5-Nitro-2-chloroiodobenzene; 4-Iodo-3-chloronitrobenzene; Benzene, 1-chloro-2-iodo-5-nitro-; (3-Chloro-4-iodophenyl)nitro compound
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Iodonitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.