Description

4,5-Dimethoxybenzocyclobutene-1-Carboxylic Acid is a high-value, multifunctional organic building block characterized by its strained benzocyclobutene core and carboxylic acid functionality. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecular architectures where its unique reactivity profile is leveraged. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry, polymer synthesis, and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targets and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators due to its bioactive scaffold.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating high-performance polymers, liquid crystals, and advanced organic electronic materials.
• Ligand & Catalyst Development: Employed in the design of novel chiral ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags, photoaffinity labels, and other molecular probes.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, including cycloaddition reactions and ring-opening transformations.

Basic Information

Product Name	4,5-Dimethoxybenzocyclobutene-1-Carboxylic Acid
CAS No.	41234-23-5
Molecular Formula	C11H10O4
Molecular Weight	206.19 g/mol
Synonyms	1,2-Dihydro-4,5-dimethoxybenzocyclobutene-1-carboxylic acid; 4,5-Dimethoxy-1-benzocyclobutene-1-carboxylic acid; 4,5-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid; BCB-COOH derivative; DMBCA; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 4,5-Dimethoxybenzocyclobutene-1-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.