Description

3-(Chloromethyl)Pyridazine is a versatile heterocyclic building block featuring a reactive chloromethyl group attached to a pyridazine ring. This compound is of significant value in organic synthesis, particularly in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for constructing more complex molecular architectures. It is primarily sought after by research chemists and process development scientists for applications in medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, dyes, and photoactive compounds.
• Cross-Coupling Reactions: The chloromethyl group can be utilized in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Nucleophilic Substitution Scaffold: Acts as an electrophilic center for reactions with amines, thiols, and other nucleophiles to introduce functional diversity.

Basic Information

Product Name	3-(Chloromethyl)Pyridazine
CAS No.	41227-72-9
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	3-(Chloromethyl)pyridazine; Pyridazine, 3-(chloromethyl)-; 3-Chloromethylpyridazine; (Chloromethyl)pyridazine; 3-Pyridazinecarbaldehyde, chloro-; 41227-72-9; 3-(Chloromethyl)-1,2-diazine
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)Pyridazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.