Description

(S)-γ-Hexanolactone is a high-purity, chiral lactone compound, also known as (S)-γ-Hexalactone. This enantiomerically pure material is valued for its specific stereochemistry, which is critical for applications requiring precise molecular orientation, such as in advanced pharmaceutical synthesis and specialty fragrance creation. It serves as a key chiral building block and flavor/fragrance ingredient for research institutions, fine chemical manufacturers, and flavor & fragrance houses seeking high-quality, optically active intermediates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Used as a key building block for the production of active pharmaceutical ingredients (APIs) and other bioactive molecules where the (S)-configuration is required.
• Flavor and Fragrance Ingredient: Imparts creamy, coconut-like, and sweet aromatic notes in premium fragrance compositions and high-value flavor formulations.
• Asymmetric Synthesis: Serves as a starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral molecules.
• Research & Development: Utilized in academic and industrial R&D for studying stereoselective reactions, developing new synthetic methodologies, and creating novel compounds.
• Fine Chemical Production: Acts as a precursor for the manufacture of other specialty chemicals, including agrochemicals and advanced materials.
• Standard for Analytical Purposes: Used as a reference standard in chromatographic analysis (e.g., GC, HPLC) for quality control and method development.

Basic Information

Product Name	(S)-γ-Hexanolactone
CAS No.	41035-07-8
Molecular Formula	C₆H₁₀O₂
Molecular Weight	114.14 g/mol
Synonyms	(S)-γ-Hexalactone; (S)-4-Methyl-γ-valerolactone; (S)-5-Methyldihydrofuran-2(3H)-one; (S)-Hexano-1,4-lactone; (S)-4-Methylpentanolide; (S)-Tetrahydro-6-methyl-2H-pyran-2-one; (S)-γ-Caprolactone (isomer); L-γ-Hexanolactone
EINECS	Contact for details

Quality Control

Our (S)-γ-Hexanolactone is produced under a strict quality management system. Each batch is thoroughly characterized and tested to ensure identity, purity, and enantiomeric excess meet the required specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, chiral purity, and impurity profile. We support compliance with cGMP and other relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Refractive Index	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.