Description

Propargyl Triflate is a highly reactive organotriflate ester, serving as a versatile trifluoromethanesulfonate (triflate) transfer reagent. Its value lies in its exceptional leaving group ability, enabling efficient alkylation and functional group transformations under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing complex molecular architectures and introducing propargyl moieties.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the propargyl group into target molecules, facilitating the development of new drug candidates.
• Agrochemical Production: Used in the synthesis of specialized pesticides and herbicides that require propargyl ether or ester functionalities.
• Cross-Coupling Reactions: Acts as an effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Negishi) for carbon-carbon bond formation.
• Polymer Science: Employed as a monomer or modifier in the synthesis of specialty polymers with tailored properties.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts containing alkyne groups.
• Organic Synthesis Research: A valuable tool in academic and industrial R&D for exploring new reaction methodologies and synthesizing complex natural products.

Basic Information

Product Name	Propargyl Triflate
CAS No.	41029-46-3
Molecular Formula	C4H3F3O3S
Molecular Weight	188.12 g/mol
Synonyms	Trifluoromethanesulfonic Acid Propargyl Ester; Propargyl Trifluoromethanesulfonate; 2-Propynyl Triflate; 2-Propynyl Trifluoromethanesulfonate; Propargyl Trifluoromethanesulphonate; Propargyl TfO; 2-Propyn-1-yl Triflate; Propargyl Ester of Triflic Acid
EINECS	Contact for details

Quality Control

Our Propargyl Triflate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity and assay. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.