Description

(S)-2,2'-Binaphthyl-20-Crown-6 is a chiral crown ether derivative, specifically an enantiomerically pure (S)-configured host molecule. This compound is highly valued for its exceptional ability to selectively bind and recognize chiral ammonium ions and other cationic species, making it a cornerstone in asymmetric synthesis and molecular recognition studies. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise chiral discrimination and separation.

Application

• Chiral Phase-Transfer Catalyst (PTC): Enables enantioselective alkylation, epoxidation, and other key transformations in asymmetric synthesis.
• Chiral Stationary Phase (CSP) Component: Used in High-Performance Liquid Chromatography (HPLC) and capillary electrophoresis for the resolution of enantiomers.
• Molecular Sensor & Recognition: Acts as a selective host in chemosensors for the detection of biologically important amines, amino acids, and pharmaceuticals.
• Asymmetric Membrane Transport: Facilitates the selective transport of chiral ions across liquid membranes for separation processes.
• Organocatalysis: Serves as a chiral scaffold or ligand in various organocatalytic reactions.
• Academic & Industrial R&D: A fundamental tool for studying host-guest chemistry, supramolecular assembly, and developing new chiral technologies.

Basic Information

Product Name	(S)-2,2'-Binaphthyl-20-Crown-6
CAS No.	41024-92-4
Molecular Formula	C₃₄H₃₂O₆
Molecular Weight	536.62 g/mol
Synonyms	(S)-(-)-2,2'-Binaphthyl-20-crown-6; (S)-1,1'-Bi-2-naphthol 20-crown-6 ether; (S)-BINOL-20-Crown-6; (S)-1,1'-Binaphthalene-2,2'-diyl 20-crown-6; (S)-BINAP-Crown-6; (S)-Enantiomer of Binaphthyl Crown Ether; (S)-Chiral Crown Ether 20-C-6; (S)-2,2'-Dihydroxy-1,1'-binaphthyl-20-crown-6
EINECS	Contact for details

Quality Control

Our (S)-2,2'-Binaphthyl-20-Crown-6 is manufactured under strict quality protocols to ensure high enantiomeric purity and chemical integrity, critical for sensitive chiral applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as enantiomeric excess (ee), purity, and identity. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.