Description

(S)-2-Amino-4-Methyl-1-(Pyrrolidin-1-Yl)Pentan-1-One Hydrochloride is a high-purity chiral intermediate and building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which are critical for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly within medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential protease inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used as a building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Asymmetric Synthesis: Serves as a precursor or reagent in stereoselective synthesis routes to create enantiomerically pure compounds.
• Peptidomimetic Development: Its structure makes it valuable for designing and synthesizing peptide analogs and mimetics with enhanced stability or bioavailability.
• Chemical Biology Probes: Can be utilized in the synthesis of labeled compounds or probes for studying biological mechanisms and target engagement.
• Process Chemistry: Investigated for use in scalable synthetic routes for the commercial production of chiral pharmaceuticals under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	(S)-2-Amino-4-Methyl-1-(Pyrrolidin-1-Yl)Pentan-1-One Hydrochloride
CAS No.	40847-07-2
Molecular Formula	C11H23ClN2O
Molecular Weight	234.77 g/mol
Synonyms	(S)-2-Amino-4-methyl-1-(pyrrolidin-1-yl)pentan-1-one hydrochloride; L-Leucine, pyrrolidide, hydrochloride; L-Leucine pyrrolidamide hydrochloride; (S)-1-(1-Oxo-4-methyl-1-(pyrrolidin-1-yl)pentan-2-yl)amine hydrochloride; 40847-07-2; (S)-2-Amino-4-methyl-1-(1-pyrrolidinyl)-1-pentanone hydrochloride; L-Leucine pyrrolidine amide hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-4-Methyl-1-(Pyrrolidin-1-Yl)Pentan-1-One Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.