Description

(2R,3S,4S,5S)-2-(2,3-Dihydro-1H-Indol-1-Yl)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol is a high-purity, chiral carbohydrate derivative featuring an indoline moiety, making it a valuable advanced pharmaceutical intermediate and building block for complex organic synthesis. Its defined stereochemistry is critical for applications requiring precise molecular recognition, such as in the development of glycosidase inhibitors and receptor-targeted therapeutics. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in producing novel active pharmaceutical ingredients (APIs) and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel glycosidase inhibitors and other therapeutic agents.
• Glycobiology Research: Used as a substrate or inhibitor in enzymatic studies related to carbohydrate metabolism.
• Chemical Biology Probe Development: Serves as a building block for creating molecular probes to study biological recognition processes.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(2R,3S,4S,5S)-2-(2,3-Dihydro-1H-Indol-1-Yl)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
CAS No.	40837-51-2
Molecular Formula	C14H19NO5
Molecular Weight	281.30 g/mol
Synonyms	1-(β-D-Glucopyranosyl)indoline; 1-(β-D-Glucosyl)indoline; Indolin-1-yl β-D-glucopyranoside; 1-(β-D-Glucopyranosyl)-2,3-dihydro-1H-indole; 1H-Indol-1-yl β-D-glucopyranoside (incorrect tautomer reference); β-D-Glucopyranosylindoline; 1-(β-D-Glucosyl)-2,3-dihydroindole
EINECS	Contact for details

Quality Control

Our production of (2R,3S,4S,5S)-2-(2,3-Dihydro-1H-Indol-1-Yl)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol adheres to stringent GMP principles and is supported by a comprehensive analytical control strategy. Every batch is characterized by advanced techniques including HPLC, NMR, and optical rotation to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and regulatory compliance for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided per COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.