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Methyl 2,3-o-Isopropylidene-6-o-Tosyl-α-D-Mannofuranoside CAS NO 40789-24-0


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CAS No.:40789-24-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl 2,3-o-Isopropylidene-6-o-Tosyl-α-D-Mannofuranoside is a key protected carbohydrate intermediate, specifically a mannose derivative with orthogonal protecting groups. This compound is essential for its role in the controlled, stepwise synthesis of complex oligosaccharides and glycoconjugates. It is primarily required by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the development of novel therapeutics and diagnostics.

Application

  • Glycosylation Reactions: Serves as a crucial mannosyl donor or acceptor in the synthesis of oligosaccharides and glycans.
  • Pharmaceutical Intermediate: Used in the research and development of carbohydrate-based drugs, including antiviral and anticancer agents.
  • Glycoconjugate Synthesis: A building block for creating glycoproteins, glycolipids, and other biologically active conjugates.
  • Chemical Biology Probes: Utilized in the preparation of labeled sugars for studying carbohydrate-protein interactions and metabolic pathways.
  • Enzyme Substrate Studies: Acts as a substrate or inhibitor for glycosidases and glycosyltransferases in biochemical research.
  • Material Science: Potential precursor for synthesizing functionalized polymers or surfaces with carbohydrate motifs.

Basic Information

Product Name Methyl 2,3-o-Isopropylidene-6-o-Tosyl-α-D-Mannofuranoside
CAS No. 40789-24-0
Molecular Formula C17H24O8S
Molecular Weight 388.43 g/mol
Synonyms Methyl 2,3-O-Isopropylidene-6-O-tosyl-α-D-mannofuranoside; 6-O-(p-Tolylsulfonyl)-1,2:5,6-di-O-isopropylidene-α-D-mannofuranose (related isomer); Methyl 6-O-tosyl-2,3-O-isopropylidene-α-D-mannofuranoside; α-D-Mannofuranoside, methyl 2,3-O-(1-methylethylidene)-6-O-(4-methylphenyl)sulfonyl-; Protected Mannose Derivative; Tosyl Mannose Acetonide
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Quality Control

Our Methyl 2,3-o-Isopropylidene-6-o-Tosyl-α-D-Mannofuranoside is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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