Description

1A,2,3,3A,8B,8C-Hexahydro-8-Hydroxy-1,1,3A-Trimethyl-6-Pentyl-1H-4-Oxabenzo[F]Cyclobut[Cd]Indene-7-Carboxylic Acid is a complex, high-purity synthetic cannabinoid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical reference standard and pharmacological research chemical for studying cannabinoid receptor interactions and metabolic pathways. It is primarily needed by research institutions, analytical laboratories, and pharmaceutical companies engaged in the development of novel therapeutics targeting the endocannabinoid system.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified material for analytical method development, validation, and quality control in drug discovery pipelines.
• Biochemical Research: Serves as a key ligand in in vitro assays to investigate binding affinity and functional activity at cannabinoid receptors (CB1/CB2).
• Metabolic Pathway Studies: Employed in preclinical research to understand the biotransformation and pharmacokinetic profile of synthetic cannabinoid analogs.
• Analytical Chemistry: Essential for calibrating equipment (HPLC, GC-MS, LC-MS) and as a system suitability check in forensic and clinical toxicology laboratories.
• Medicinal Chemistry: Acts as a sophisticated chemical intermediate or precursor for the synthesis of novel cannabinoid-based drug candidates with modified therapeutic profiles.
• Regulatory Compliance & Safety Testing: Provides a definitive standard for the identification and quantification of this specific compound in compliance and safety assessment studies.

Basic Information

Item	Details
Product Name	1A,2,3,3A,8B,8C-Hexahydro-8-Hydroxy-1,1,3A-Trimethyl-6-Pentyl-1H-4-Oxabenzo[F]Cyclobut[Cd]Indene-7-Carboxylic Acid
CAS No.	40524-99-0
Molecular Formula	C24H32O4
Molecular Weight	384.51 g/mol
Synonyms	JWH-018 N-(5-Hydroxypentyl) Metabolite; JWH-018 5-Hydroxypentyl Metabolite; 1-Pentyl-3-(1-naphthoyl)indole 5-Hydroxypentyl Metabolite; JWH 018 5-OH Metabolite; 5-Hydroxy-JWH-018; JWH-018 5-Hydroxypentyl Analog; [1-(5-Hydroxypentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone (related core structure); Cannabinoid Receptor Agonist Metabolite Standard
EINECS	Contact for details

Quality Control

Our production of this advanced research chemical adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for assay, related substances, and residual solvents is provided with each shipment. We support compliance with GLP (Good Laboratory Practice) standards for research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.