Description

p-(Methylsulfonyl)Benzyl Chloride is a high-value, reactive organic intermediate featuring a benzyl chloride group and a para-methylsulfonyl substituent. This unique structure makes it a critical building block for synthesizing more complex molecules in advanced chemical research and manufacturing. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators where the methylsulfonyl and benzyl motifs are pharmacologically relevant.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactivity to introduce the benzyl chloride moiety into active molecules.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Research: Employed in polymer chemistry and material science to incorporate sulfone and reactive chloride functionalities into polymers or small molecules for advanced material properties.
• Custom Synthesis and Contract Manufacturing: An essential reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	p-(Methylsulfonyl)Benzyl Chloride
CAS No.	40517-43-9
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	4-(Chloromethyl)phenyl methyl sulfone; 1-(Chloromethyl)-4-(methylsulfonyl)benzene; p-(Chloromethyl)phenyl methyl sulfone; 4-Methylsulfonylbenzyl chloride; (4-Methylsulfonylphenyl)methyl chloride; α-Chloro-4-(methylsulfonyl)toluene; 40517-43-9
EINECS	Contact for details

Quality Control

Our p-(Methylsulfonyl)Benzyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.