Description

3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid is a versatile carboxylic acid derivative featuring a tetrahydropyran ring, making it a valuable chiral building block and intermediate in organic synthesis. Its unique structure provides a rigid, oxygen-containing scaffold that is crucial for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the tetrahydropyran moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of specialty monomers for polymers with specific thermal or mechanical properties.
• Flavor and Fragrance Chemistry: Acts as an intermediate for creating complex aroma chemicals and flavor compounds.
• Academic and R&D Laboratories: Used in methodological studies and the discovery of new synthetic routes in organic chemistry.

Basic Information

Product Name	3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid
CAS No.	40500-10-5
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	4-(2-Carboxyethyl)tetrahydro-2H-pyran; 3-(Oxan-4-yl)propanoic acid; Tetrahydro-4-(2-carboxyethyl)-2H-pyran; 3-(Tetrahydropyran-4-yl)propionic acid; 40500-10-5; THP-Propanoic Acid; 4-(2-Carboxyethyl)tetrahydropyran
EINECS	Contact for details

Quality Control

Our 3-(Tetrahydro-2H-Pyran-4-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.