Description

2-Methyl-2-Phenyl-Cyclopropanecarboxylic Acid is a high-purity cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique sterically hindered structure makes it a valuable intermediate for constructing complex molecular architectures with defined stereochemistry. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its cyclopropane ring contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A versatile building block in methodological chemistry research for studying cyclopropanation reactions and ring-strain chemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and flavors & fragrances requiring high-purity intermediates.

Basic Information

Product Name	2-Methyl-2-Phenyl-Cyclopropanecarboxylic Acid
CAS No.	40474-21-3
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	2-Phenyl-2-methylcyclopropanecarboxylic acid; (±)-trans-2-Methyl-2-phenylcyclopropanecarboxylic acid; 2-Methyl-2-phenylcyclopropanecarboxylic acid; α-Methyl-α-phenylcyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 2-methyl-2-phenyl-; NSC 163022; 2-Phenyl-2-methyl-1-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and every batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.