Description

Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid is a specialized, high-purity carboxylic acid derivative of a hydrogenated indene structure, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its unique, rigid bicyclic framework makes it invaluable for synthesizing complex molecules with precise stereochemistry, particularly in active pharmaceutical ingredients (APIs). This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its structural rigidity contributes to target specificity.
• Fine Chemical Building Block: Employed in asymmetric synthesis and catalysis for creating complex, high-value specialty chemicals.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in stereoselective reactions.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and medicinal chemistry research.

Basic Information

Product Name	Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid
CAS No.	40252-86-6
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	2-Carboxy-1,2,3,4,4a,5,6,7-octahydro-4,7-methano-1H-indene; Bicyclo[2.2.1]heptane-2-carboxylic acid, 1,3,3-trimethyl- (9CI); 1,3,3-Trimethylbicyclo[2.2.1]heptane-2-carboxylic acid; 2-Norbornanecarboxylic acid, 1,3,3-trimethyl-; Hydrodicyclopentadienecarboxylic Acid; Trimethylnorcamphorcarboxylic Acid; Contact for details on additional trade names.
EINECS	254-879-8

Quality Control

Our Octahydro-4,7-Methano-1H-Indene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The container must be kept tightly closed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Purity (Chiral HPLC)	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.