Description

(-)-Menthoxyacetic Acid CAS NO 40248-63-3 is a chiral, non-racemic organic acid derivative of menthol, valued for its role as a versatile synthetic intermediate and building block. Its specific stereochemistry and functional groups make it a critical precursor in the synthesis of high-value, optically active compounds. This product is essential for research and industrial applications in the pharmaceutical, agrochemical, and flavor & fragrance sectors, where precise molecular configuration is paramount for efficacy and sensory properties.

Application

• Pharmaceutical Intermediate: Key chiral building block for synthesizing active pharmaceutical ingredients (APIs), particularly in projects requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the (-)-enantiomer can provide targeted biological activity.
• Flavor and Fragrance Ingredient: Serves as a precursor for modifying and creating novel minty, cooling, or fresh odorants and taste modifiers.
• Asymmetric Catalyst Ligand: Employed in the development of chiral ligands for metal-catalyzed asymmetric synthesis reactions.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex natural products and specialty chemicals.
• Liquid Crystal and Advanced Material Precursor: Potential use in synthesizing chiral dopants for liquid crystal displays (LCDs) and other functional materials.

Basic Information

Product Name	(-)-Menthoxyacetic Acid
CAS No.	40248-63-3
Molecular Formula	C₁₃H₂₄O₃
Molecular Weight	228.33 g/mol
Synonyms	(-)-Menthoxyacetic Acid; L-Menthoxyacetic Acid; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyloxyacetic Acid; (1R,2S,5R)-Menthoxyacetic Acid; p-Menth-3-yloxyacetic Acid; L-Menthyloxyacetic Acid; (-)-Menthyl Glycolic Acid Ether; NSC 403796
EINECS	254-879-9

Quality Control

Our (-)-Menthoxyacetic Acid is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet stringent specifications. We provide comprehensive Certificates of Analysis (COA) with data from advanced analytical techniques, including HPLC, GC, and chiral analysis. Our quality commitment supports applications requiring high chiral purity and reliable batch-to-batch consistency for GMP and research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccant or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.