Description

6-Selenoinosine is a specialized nucleoside analog where the oxygen atom in the 6-position of the purine ring is replaced by selenium, creating a unique selenoether linkage. This structural modification is of significant interest in biochemical research and pharmaceutical development, particularly for studying enzyme mechanisms and exploring novel therapeutic agents. It serves as a critical intermediate and research tool for scientists in medicinal chemistry, biochemistry, and molecular biology who are investigating nucleoside metabolism, antiviral strategies, and selenium's role in biological systems.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for purine nucleoside phosphorylase and other nucleoside-metabolizing enzymes.
• Medicinal Chemistry Intermediate: Serves as a key building block for the synthesis of novel selenium-containing nucleoside analogs with potential antiviral or anticancer activity.
• Mechanistic Probes: Employed to study the role of chalcogen atoms (O, S, Se) in enzyme binding and catalysis due to its altered electronic and steric properties.
• Selenium Biology Studies: Acts as a tool compound to investigate the incorporation and metabolism of selenium in nucleic acid contexts.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical R&D laboratories.

Basic Information

Product Name	6-Selenoinosine
CAS No.	40093-99-0
Molecular Formula	C10H12N4O4Se
Molecular Weight	339.19 g/mol
Synonyms	6-Selenoinosine; 6-Se-Inosine; 9-β-D-Ribofuranosyl-6-selenopurine; 6-Seleno-9H-purin-6-one, 9-β-D-ribofuranosyl-; Inosine, 6-seleno-; 6-Selenopurine riboside; 6-Se-Purine riboside
EINECS	Contact for details

Quality Control

Every batch of 6-Selenoinosine is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere if long-term stability is required. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.