Description

Piperidine-4-Carboxylic Acid (2-Hydroxy-Propyl)-Amide is a high-purity, versatile piperidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a piperidine core and a hydroxypropyl amide side chain, makes it a valuable intermediate for constructing complex molecules with targeted pharmacological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the piperidine moiety can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to modify the properties of specialty polymers and resins.
• Chemical Research: A versatile building block for academic and industrial research in medicinal chemistry and chemical biology.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and other high-value intermediates.

Basic Information

Product Name	Piperidine-4-Carboxylic Acid (2-Hydroxy-Propyl)-Amide
CAS No.	40051-34-1
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	4-Piperidinecarboxamide, N-(2-hydroxypropyl)-; N-(2-Hydroxypropyl)isonipecotamide; 1-(2-Hydroxypropylcarbamoyl)piperidine-4-carboxylic acid (tautomer); 4-Carbamoylpiperidine, N-(2-hydroxypropyl)-; Isonipecotamide, N-(2-hydroxypropyl)-; (2-Hydroxypropyl)amide of piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our Piperidine-4-Carboxylic Acid (2-Hydroxy-Propyl)-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.