Description

2-Hydroxy-3-Butynoic Acid is a versatile bifunctional organic compound featuring both a hydroxyl group and a terminal alkyne within a short carbon chain, making it a valuable building block in synthetic chemistry. Its unique structure enables it to serve as a key intermediate for the synthesis of complex molecules, including pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly sought after by research institutions and industrial manufacturers in the pharmaceutical, fine chemical, and material science sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing complex drug molecules, particularly those requiring alkyne or propargylic alcohol moieties for click chemistry or further functionalization.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactive groups allow for the creation of novel bioactive compounds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for synthesizing specialty polymers with tailored properties, such as conductive materials or hydrogels.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals requiring precise molecular architecture.
• Bioconjugation & Probe Development: Utilized in biochemical research for labeling biomolecules via its alkyne group in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing heterocyclic compounds.

Basic Information

Product Name	2-Hydroxy-3-Butynoic Acid
CAS No.	40027-75-6
Molecular Formula	C₄H₄O₃
Molecular Weight	100.07 g/mol
Synonyms	3-Butynoic acid, 2-hydroxy-; 2-Hydroxybut-3-ynoic acid; 3-Butyn-2-ol-1-carboxylic acid; Propargylglycolic acid; Terminal alkyne glycolic acid derivative; 2-Hydroxy-3-butynoate; 40027-75-6 (CAS Registry)
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3-Butynoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific tests is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.