Description

H-Tyr-NH2 HCl is a protected derivative of the amino acid tyrosine, specifically the amide of the C-terminus with the N-terminus protected as a hydrochloride salt. This compound is a crucial building block in peptide synthesis, offering precise control over the molecular structure for research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, biochemistry, and peptide-based drug discovery.

Application

• Peptide Synthesis: A key protected amino acid intermediate for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the development and study of novel therapeutic peptides and peptidomimetics.
• Bioconjugation: Serves as a precursor for creating tyrosine-containing linkers or tags for protein and antibody labeling.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate tyrosine-related metabolic pathways.
• Reference Standard: Acts as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	H-Tyr-NH2 HCl
CAS No.	4985-46-0
Molecular Formula	C9H13N2O2•HCl
Molecular Weight	216.67 g/mol
Synonyms	L-Tyrosinamide Hydrochloride; Tyrosinamide HCl; H-Tyr-NH2•HCl; (S)-2-Amino-3-(4-hydroxyphenyl)propanamide hydrochloride; Fmoc-Tyr-NH2 HCl (when referring to the N-Fmoc protected form); Boc-Tyr-NH2 HCl (when referring to the N-Boc protected form); 4-Hydroxy-L-phenylalaninamide hydrochloride; L-Tyrosine amide hydrochloride
EINECS	225-635-2

Quality Control

Our H-Tyr-NH2 HCl is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can supply material meeting specifications for general laboratory use or tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-8.0° to -12.0° (c=1 in 1N HCl)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.