Description

S-Methyl 4-Methylbenzenethiosulfonate is a specialized organosulfur compound, also known as S-Methyl p-toluenethiosulfonate, with the CAS number 4973-66-4. This chemical serves as a versatile and valuable methylthiolating agent and synthetic intermediate in advanced organic synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thioether or sulfone functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the introduction of a methylthio group is required.
• Material Science Research: Employed in the development of novel polymers, ligands, and functional materials with specific sulfur-based properties.
• Organic Methodology Development: A reagent of choice in academic and industrial R&D for studying new thiolation and sulfenylation reactions.
• Peptide and Protein Modification: Useful for selective modification of cysteine residues in biochemical research.
• Cross-Coupling Reagent: Acts as an electrophilic sulfur source in transition metal-catalyzed cross-coupling reactions.

Basic Information

Product Name	S-Methyl 4-Methylbenzenethiosulfonate
CAS No.	4973-66-4
Molecular Formula	C8H10O2S2
Molecular Weight	202.29 g/mol
Synonyms	S-Methyl p-toluenethiosulfonate; Methyl p-toluenethiosulfonate; p-Tolyl methyl thiosulfonate; 4-Methylbenzenesulfonothioic acid S-methyl ester; Methyl 4-methylphenyl thiosulfonate; Toluenesulfonothioic acid S-methyl ester; (4-Methylphenyl)sulfonothioic acid S-methyl ester
EINECS	225-618-5

Quality Control

Our S-Methyl 4-Methylbenzenethiosulfonate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for your critical syntheses. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.