Description

Thiophosphoric Acid O,o-Diethyl o-(Coumarin-3-Yl) Ester is a specialized organophosphorus compound featuring a coumarin moiety, which imparts unique photophysical and chemical properties. This compound is valued for its role as a key intermediate in the synthesis of advanced materials and biologically active molecules. It is primarily sought by research institutions and industrial manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors for developing novel products.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of advanced insecticides and pesticides, leveraging its organophosphorus structure.
• Pharmaceutical Research: Used as a building block for developing new drug candidates, particularly those exploring coumarin-based pharmacophores.
• Fluorescent Probe Synthesis: Serves as a starting material for creating sensitive fluorescent tags and sensors due to the inherent coumarin fluorophore.
• Polymer Chemistry: Employed in the development of specialty polymers and coatings with tailored properties like UV-activity or specific reactivity.
• Chemical Biology Studies: Utilized in the design of activity-based probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Acts as a functional monomer or additive in the creation of novel organic electronic materials or photoresists.

Basic Information

Product Name	Thiophosphoric Acid O,o-Diethyl o-(Coumarin-3-Yl) Ester
CAS No.	4935-28-8
Molecular Formula	C14H15O5PS
Molecular Weight	326.31 g/mol
Synonyms	Coumarin-3-yl diethyl phosphorothioate; 3-Coumarinyl diethyl phosphorothioate; Diethyl (3-coumarinyl) phosphorothioate; O,O-Diethyl O-(3-coumarinyl) phosphorothioate; Phosphorothioic acid, O,O-diethyl O-(2-oxo-2H-1-benzopyran-3-yl) ester; 3-(Diethoxyphosphinothioyloxy)coumarin; Coumaphos impurity (related compound)
EINECS	225-571-9

Quality Control

Our production of Thiophosphoric Acid O,o-Diethyl o-(Coumarin-3-Yl) Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged exposure to air should be minimized. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.