Description

3-tert-Butyl-4-Hydroxybenzonitrile is a specialized phenolic nitrile compound that serves as a versatile intermediate in advanced organic synthesis. Its molecular structure, featuring both a sterically hindered phenol and a nitrile group, makes it a valuable building block for creating high-performance materials and functional additives. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and polymer industries seeking to develop new compounds with enhanced stability and performance characteristics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring hindered phenol motifs for antioxidant properties.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where its structural components contribute to product efficacy and environmental stability.
• Polymer Additive: Acts as a monomer or stabilizer intermediate in the production of high-performance engineering plastics and specialty polymers.
• Antioxidant Precursor: Serves as a starting material for manufacturing sophisticated phenolic antioxidants used in fuels, lubricants, and plastics to prevent oxidative degradation.
• Liquid Crystal & Electronic Materials: Utilized in the research and production of advanced organic electronic materials and liquid crystal displays (LCDs) due to its rigid molecular structure.
• UV Stabilizer Synthesis: Intermediate for creating light stabilizers that protect coatings, paints, and polymers from UV-induced damage.
• Cross-coupling Reactions: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems important in material science.
• Research & Development: A valuable tool for academic and industrial chemists exploring new synthetic methodologies and novel compound libraries.

Basic Information

Item	Details
Product Name	3-tert-Butyl-4-Hydroxybenzonitrile
CAS No.	4910-04-7
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	4-Cyano-2-tert-butylphenol; 2-tert-Butyl-4-cyanophenol; 4-Hydroxy-3-tert-butylbenzonitrile; 3-(1,1-Dimethylethyl)-4-hydroxybenzonitrile; Benzonitrile, 3-(1,1-dimethylethyl)-4-hydroxy-; 3-tert-Butyl-4-hydroxy-benzonitrile; 4-Cyano-2-(tert-butyl)phenol; 2-(tert-Butyl)-4-hydroxybenzonitrile
EINECS	225-520-8

Quality Control

Every batch of 3-tert-Butyl-4-Hydroxybenzonitrile is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high purity and consistent batch-to-batch quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.